Which statement about enzyme catalyzed reactions is NOT true?

A.	enzymes form complexes with their substrates.
B.	enzymes lower the activation energy for chemical reactions.
C.	enzymes change the K eq for chemical reactions.
D.	many enzymes change shape slightly when substrate binds.
E.	reactions occur at the "active site" of enzymes, where a precise 3D orientation of amino acids is an important feature of catalysis.