LDL Tutorial
Problem 2: LDL Levels in Adults vs. Newborns
The reduction in levels of the LDL receptor in adults vs.
newborns may be explained by the observation that:
![](a-1.gif) |
High cholesterol levels in our diet reduce synthesis of
LDL receptor mRNA |
![](b-1.gif) |
Adults have more active oxidation systems that degrade
the receptor |
![](c-1.gif) | Adults synthesize proteins at a much lower rate than
newborns |
![](d-1.gif) |
Adults have more active lysosomal proteases to degrade
endocytosed material |
![](problem_1_left-2.gif)
![](human_biology.gif)
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The University of Arizona
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