A.	polycistronic mRNAs are very rare
B.	many genes are interrupted by non-coding DNA sequences
C.	RNA synthesis and protein synthesis are coupled as in prokaryotes RNA synthesis occurs in the nucleus, but translation occurs on ribosomes in the cytoplasm. Transcription and translation are spatially and temporally separated in eukaryotic cells.
D.	mRNA is often extensively modified before translation
E.	multiple copies of nuclear genes, and pseudo genes can occur