LDL Tutorial

Problem 7: Familial Hypercholesterolemia

Which of the following is NOT a mutation leading to the disease familial hypercholesterolemia?

	Loss of the gene coding for the LDL receptor
	Loss of the ability of the receptor to bind LDL particles
	Inability of the LDL receptor to localize in coated pits
	Increase of LDL receptor synthesis in the intestine leading to elevated cholesterol