B₁₂/Folate Problem set

Question 8: B₁₂deficiency

Abnormal findings in patients with a vitamin B₁₂ deficiency may include:

A. methylmalonic aciduria

B. homocystinuria

C. megaloblastic anemia

D. hypersegmented nuclei in leucocytes

E. sensory neuropathy

All five symptoms

Yes, all five! As you must have realized, a B₁₂ deficiency can also disrupt folate metabolism via the infamous "folate trap", so that the symptoms displayed by the patient are all of the symptoms of B₁₂ and folate deficiency combined.