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Question 8 of 8

A.	B. anthracis without capsule The "antiphagocytic" capsule is very important in the progression of anthrax since it protects the bacterium from being eliminated by cells of the immune system. Therefore, without the capsule B. anthracis can only multiply inside the body for a short time before the organism is eliminated by phagocytes. This allows the immune system to respond to the bacterium and form antibodies. If the vaccinated person is then infected with B. anthracis with capsule it can neutralize the toxins produced with the help of these antibodies. This vaccine was first developed by Luis Pasteur for the vaccination of domestic animals such as cattle and sheep.
B.	Inactivated B. anthracis Although for many vaccines inactivated bacteria or components of the bacterial coat are used this is not the case for B. anthracis
C.	Capsule-antigens The capsule of this organism is not antigenic, which means it "hides" the organism from the immune system.
D.	Inactivated anthrax toxin Inactivated anthrax toxins could also be used for vaccination. However, todate attempts to use inactivated toxin as a vaccine have not been successful.