The correct operational relationship between pKa and pH is that:
A. both are log functions. B. both are always <7 for acids, and >7 for bases. C. These two concepts are not operationally related in any way since biological fluids contains mixtures of too many acids and bases. D. When pH = pKa , the compound in question will have a charge of +0.5. E. When pH = pKa , the ionizable compound in question (whether acid or base) will be half protonated and half deprotonated.
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