Human Genetics Problem Set

Problem 16: Polymorphism in Huntington's Disease gene

Which of the following describes a type of polymorphism that occurs within the gene that causes Huntington's disease?

A.	RFLPs, "restriction fragment length polymorphisms"
B.	ESTs, "expressed sequence tags"
C.	STRPs, "short tandem repeat polymorphisms" A short sequence (CAG) is repeated many times in tandem. The number of repeats varies between the normal and disease-causing alleles of the gene.
D.	STSs, "sequence tagged sites"
E.	None of the above