Human Genetics Problem Set

Problem 16: Polymorphism in Huntington's Disease gene

Which of the following describes a type of polymorphism that occurs within the gene that causes Huntington's disease?

A. RFLPs, "restriction fragment length polymorphisms"
B. ESTs, "expressed sequence tags"
C. STRPs, "short tandem repeat polymorphisms"
A short sequence (CAG) is repeated many times in tandem. The number of repeats varies between the normal and disease-causing alleles of the gene.
D. STSs, "sequence tagged sites"
E. None of the above


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