Biochemistry at The Biology Project

Carbohydrate Metabolism Regulation Problem Set

In this module, you will learn about how certain carbohydrate pathways are reciprocally affected by insulin and glucagon. The areas of focus will be:
a) regulation of glycolysis by phosphorylation/dephosphorylation of key enzymes;
b) regulation of glycogen formation vs. breakdown, again by phosphorylation/dephosphorylation;
c) how this regulation is coordinated so as to avoid futile cycling and trapping of intermediates;
d) how this regulation fits with the overall function of insulin vs. glucagon.

Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem.
  1. Liver Enzymes Affected By Insulin
  2. Enzyme Dephosphorylation By Insulin Action
  3. PFK-1 Regulation in Liver
  4. Insulin Regulation of Glucokinase
  5. Enzyme Phosphorylation Induced by Glucagon
  6. Epinephrine action to mobilize glycogen
  7. A secondary action of epinephrine in liver
  8. Insulin action in (skeletal) muscle

[Biochemistry] [Vocabulary] The Biology Project

The Biology Project
The University of Arizona
Revised: May 11, 2000
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