Using Computers to Study Molecular Structure

Peptide Bonds

About peptide bonds

Proteins are formed from amino acids linked together in end-to-end fashion. The carboxyl group of one amino acid condenses with the alpha amino group of the next via the peptide bond.

Choose a few peptides from the list below for viewing. For each peptide, identify, for yourself, the individual amino acids, the peptide bond, and the two ends of the molecule. These are known as the "amino terminal" and the "carboxyl terminal" ends. HINT: Try viewing the molecules in wire-frame mode.

Opening peptide files in MacMolecule

When you choose a peptide from the list below, MacMolecule will automatically open that peptide file. You can switch back to Netscape by choosing Netscape from the Applications Menu.

Peptide MacMolecule Files

alpha-L-glu-L-glu

L-ala-L-ala-L-ala

L-trp-L-met-L-asp-L-phe

Questions

3. TRUE or FALSE:
When a peptide bond is formed, the two alpha carbons of the linked amino acids, along with the C, O and N atoms of the actual peptide bond, all lie in the same plane.
4. TRUE or FALSE:
The R-groups of different amino acids in a peptide are linked directly to each other by covalent bonds.



The Biology Project
University of Arizona
Wednesday, September 9, 1998
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