Regulation of Carbohydrate Metabolism Problem Set

Question 4: Insulin Regulation of Glucokinase

Glucokinase is also regulated by insulin in liver, but not via phosphorylation. How is this regulation accomplished?

A.	Via increased transcription of the gene encoding this enzyme
B.	By recruitment of pre-existing enzyme from the Golgi
C.	Via allosteric regulation by fructose-2,6-bisphosphatase
D.	Activation by association with IRS-1
E.	An inhibitory subunit of the enzyme dissociates after binding cAMP